!!!!! IMPORTANT READ !!!! Aspartame Inflames Coronavirus And Is Clearly Implicated In Pulmonary Distress... 'Shortness Of Breath'

https://rense.com/general96/aspartame-inflames-coronavirus.php

Aspartame Inflames Coronavirus And Is Clearly Implicated In Pulmonary Distress... 'Shortness Of Breath'

By Dr. Betty Martini, D.Hum. 3-30-20

Corona viruses are a large family of viruses which may cause illness in animals or humans.  In humans, several corona viruses are known to cause respiratory infections ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The most recently discovered corona virus  causes corona virus disease COVID-19.  What if you are using aspartame? It has many names from NutraSweet and 951 to Neotame, Advantame, Benevia, Canderel, AminoSweet, Spoonful, etc.  By law, it requires a PKU warning for those who cannot metabolize phenylalanine which is 50% of the molecule.  So, if you see "contains phenylalanine" and warnings that phenylketonurics must not use it, it's a dead giveaway it probably has aspartame in it.    Aspartame is an excitoneurotoxic, carcinogenic, genetically-engineered drug, an adjuvant and teratogen.  As neurosurgeon Dr. Russell Blaylock once said in a lecture:  "Understand the reactions are not allergic but toxic like arsenic and cyanide."  It damages the mitochondria, the power house of the cell and interacts with drugs and vaccines.  Symptoms of COVID-19 are fever, tiredness and dry cough. Some patients may have aches and pains, nasal congestion, runny nose, sore throat or diarrhea. Around 1 out of every 6 people who gets COVID-19 becomes seriously ill and develops difficulty breathing..  So, the LAST thing someone with the virus needs to be consuming is a product that causes shortness of breath.  It is my personal opinion it may not only make the virus worse but people on aspartame who become infected with this coronavirus may not make it.  I've seen many cases that appeared to be aspartame cases...and the patient died of the virus.  Or, WITH the virus and not because of it.  World expert H. J. Roberts, M.D. has passed on but left a treasury of medical documents.   Here is his information on shortness of breath from the medical text, "Aspartame Disease: An Ignored Epidemic", 1000 pages of diseases and horrors, page 404 through 406:  SHORTNESS OF BREATH  "The frequency of "shortness of breath"  (dyspnea) in patients consuming aspartame who did not have underlying heart or lung disorders was surprising.  Specifically, 110 (9 percent) experienced this symptom.  It predictably abated when they avoided aspartame products.  For example, a 72 year old woman reported, "My chest felt like it was stuffed," after using ATS for two weeks.  She "felt almost back to normal" within several days after stopping this product.  Several observations are noteworthy.  "Several aspartame reactors described the prompt onset of choking and shortness of breath after chewing aspartame gum ("choker gum").  This was mistaken for a "seizure" in one instance.  "One patient was observed to have swelling of the larynx.  "Decreased secretions in the upper respiratory passages, comparable to "dry eyes" (Chapter IV) and "dry mouth" (Chapter IX-F, may contribute tothe pulmonary symptoms.  "An aspartame reactor developed severe choking while drinking a diet soda on a plane as it climbed to high  attitude.  "The occurrence of sleep apnea in aspartame users was discussed in Chapter VI-K  "The FDA noted receiving complaints of "difficulty breathing" from 112 consumers in its April 20, 1995 report.  "The cause and significance of this feature remain puzzling.  In the absence of asthma and other allergic features (Chapter VIII) the dyspnea presumably reflects neurotransmitter dysfunction within the brain's respiratory center.  Representative Case Reports  Case IX-C-1  "A 40-year-old woman stressed that she previously did "not have any problems I cannot handle".  She wrote:  "Help!  Last week, I was fortunate to hear you on WWDB radio. I just came home from the hospital.  I was in intensive care for two days.  (They said I may have a clot on my lung.)  After two days they said I did not have a clot, and did not know what was wrong with me.  They gave me many tests.  "My symptoms over the last three months have been shortness of breath (I get up in the middle of the night gasping), blurred vision, dizziness, headache, falling (I fell in Center City drunk).  I have been to many doctors, and they cannot seem to find what is wrong.  "I called my family doctor when I heard you last week because I drank six to eight glasses of diet cola each day for three years.  He said he would look into it."  Case IX-C-16  "A 35-year-old woman developed "shortness of breath" that persisted.  She consulted a number of physicians who variously told her that the cause was stress (despite an exemplary personal and professional life), atypical asthma, and a swollen larynx.  Other symptoms included weight gain, hair loss, dizziness, irritability, fatigue, heavy menstrual bleeding,  abdominal pain, and dryness of the skin.  See also had hypothyroidism.  "The patient probed every aspect of her diet and environmental contacts as her breathing problem intensified.  She wrote, "Can you imagine my anxiety at waking up and still not being able to breath?  The only unusual aspect of her routine was the daily use of a gum flavored with aspartame.  She wrote  "I already spent a small fortune on tests that included asthma studies, upper/lower GIs, ultrasounds, x-rays, blood work, cholesterol, and heart, lung and gynecologic testing.  I even considered seeing a psychiatrist.  I then stopped using this gum, and felt relief almost immediately.  I retested myself numerous times to see if I had really found the answer.  I am completely assured that the aspartame caused all my problems.  At one later time, I consumed a diet soda, not knowing that they had switched from saccharin to aspartame.  Within the hour, I could not catch my breath."  Case IX-C-17  A female athlete had run from five to 13 miles daily for eight years without incident.  Concerned about her weight, she began drinking diet sodas.  She then experienced difficulty in breathing while on the treadmill.  A physician diagnosed asthma.  When numerous   x-rays and other studies failed to reveal a cause, the issue of "stress" was raised... to her dismay.  Other features included severe headache, memory loss, impairment of vision, numbness/tingling in the extremities, a rapid heart rate, and pain in the joints.  This patient happened to see a flyer on the aspartame disease when she went to purchase a 24 pack of diet soda.  As she read the convincing details, "I almost began to cry."  This is the end of Dr. Robert's discussion on shortness of breath.  Dr. Francis A. Boyle, on the Corona Virus -  this man has impeccable credentials:   http://www.just-international. org/articles/dr-francis-boyle- creator-of-bioweapons-act- says-coronavirus-is- biological-warfare-weapon/      He wrote to me "The FDA is up to its eyeballs in Nazi Biological Warfare Death Science Dirty Work on Covid. See the UNC/Wuhan BSL4 research article on coronavirus where FDA is clearly listed as one of the participants in my Smoking Gun interview that you can find on google.  Francis A. Boyle. YouTube, Channel: Insights World Views at  https://www.youtube.com/watch? v=iLnyOB1M8cg  Former FDA Commissioner Herbert L. Lay, Jr., once said:  "I am not going to tell you that the FDA has not devised the perfect system for keeping hazardous chemicals out of our foods.  You'll simply have to live with it."    Here is another one:    https://www.veteranstoday.com/ 2020/03/27/pravda-us-army- created-covid-19-in-2015- research-proofs-or-debunking- you-pick/  Here is another interview of Francis Boyle by Dr. Bill Deagle:    https://youtu.be/ MKGIP_W4L8k  For over 30 years, I've warned on the dangers of aspartame.  The horror stories would make you weep and been a victim myself.  I went to the hospital for one thing and given probably 30 medications a day for which I protested.  One powder said sucrose which is sugar so I thought it was safe.  I took it and they sent me home where I stopped breathing.  It's horrible because you can't get your breath or move to get to a phone.  My husband called 911 just in time and they  used an oxygen mask.  The powder was vanilla flavored.  Consider, I would seriously doubt the pharmaceutical industry would use expensive pure vanilla.  They use vanillin which is genetically engineered with aspartame.  Then the FDA allows Advantame on the market which is a half a molecule of aspartame with a half a molecule of vanillin which studies have shown interaction.   Once a victim has used  aspartame, they usually are chemically hypersensitive for life.   Many carry epi-pens as they may go into anaphylactic shock.  It is difficult to get victims off because of the addiction.  Methanol is classified as a narcotic.  It causes chronic methanol poisoning which affects the dopamine system of the brain and causes the addiction.  As Dr. Roberts says in his medical text, the transformation of phenylalanine to dopamine and dopamine metabolites is highly relevant. Addictive drugs flood synapses with dopamine, which carries a "pleasure message" from one nerve cell to another in the "reward pathway"...thereby creating a "high".  For instance, cocaine blocks the reuptake of dopamine, and acts as an indirect dopamine agonist.  Such repeated rushes can result in desensitization of the brain to dopamine, and perhaps a reduction of dopamine receptors.  A study was done showing aspartame depletes brain neurotransmitters up to74%.  I wrote an article about it published in the National Health Federation.   https://thenhf.com/2019/03/24/ aspartame-depletes-brain- neurotransmitters/  I think they should be highly supported since they get out the facts and are international.  Aspartame is causing all kinds of psychiatric and behavioral problems and even little children are committing suicide.  Imagine giving children an asthma drug Singulair with aspartame  causing such suffering it hurts to read the emails.  Dr. Evelyn Higgins is taking care of patients with drug interactions with aspartame giving them back their life.  She writes of a case with Singulair including neuropsychiatric problems.  Dr. Ralph Walton, psychiatrist did a study and the reactions were so severe they had to stop it when the administrator had a retinal detachment and lost his vision in one eye:  Walton, Ralph G., Robert Hudak, Ruth Green-Waite  "Adverse Reactions to Aspartame: Double-Blind Challenge in Patients from a Vulnerable Population" Biological Psychiatry, 1993:34:13-17. 19.  How bad can it get?   Just read the Trocho Study by Dr. M. Alemany which shows the formaldehyde converted from the free methyl alcohol embalms living tissue and damages DNA.  Imagine the formaldehyde seeping into the cells and in the blood stream.  Here is that  study:    http://www.mpwhi.com/ formaldehyde_from_aspartame. pdf   Dr. Woodrow Monte  wrote "While Science Sleeps:  A Sweetener Kills" and says the formaldehyde turns the tissues to plastic.  Aspartame destroys the immune system.  In the Journal Of The Diabetic Association Of India 1995 : Vol. 35, No. 4. Emerging Facts About Aspartame by Dr. J. Barua, she said:  "Persons with chronic immune system disorders are often very sensitive to low level chemical exposure including formaldehyde. As stated by the National Resource Council (1981, pg177): "In some persons not previously sensitized, repeated exposure to formaldehyde may result in the development of hypersensitivity." Fujimaki (1992) & Vojdani (1992) have shown immune system alteration from exposure to formaldehyde.  "Dr. Sherry Rogers, an expert in environmental exposure and chemical sensitivity discusses how aldehydes, especially formaldehyde can cause significant damage in the body (Rogers 1990). She lists the following symptoms found for persons exposed to urea foam formaldehyde insulation (UFFI) at levels of formaldehyde as low as 0.12 ppm: Depression, dizzy or spacey, poor memory, burning eyes or throat, fatigue, flushing of face, inability to concentrate, laryngitis, cant think straight, chronic cough, asthma, "like thinking in a fog", arthritis feel unreal, rashes, headache, heart palpitations, and much more......  Dr. Rogers cites Main (1983) where adverse health effects to formaldehyde exposure were found at levels between 0.12-1.6 ppm."  Dr. H. J. Roberts writes in his medical text that the extent to which a hyperimmune population has evolved is pertinent and disturbing.  As to the virus here is what Dr. Gary Kohl's wrote in one of his articles:  "According to the website   www.DoctorsInItaly. com  , Italy used a "new" and thus untested-for-safety-or- efficacy flu vaccine starting in September 2019. -----  " However, in September 2019 for the first time - Italy made available a cell-based flu shot, called VIQCC or QIVc. This flu vaccine is produced from animal cells rather than eggs!  "VIQCC is a quadrivalent flu vaccine that contains 2 type A viruses (H1N1 and H3N2) and 2 type B viruses. It is approved for people ages 9 and older. (To find out more, go to:  Everything You Need To Know About The Flu Shot In Italy. - January 13, 2020, at:     https://www. doctorsinitaly.com/b/flu-shot/ "Flu Shots Found to Increase the Incidence of Coronavirus Infections  "Incidentally, flu vaccines have been found to increase the risk for  coronavirus infections and other respiratory infections. Go to:  https://www.sciencedirect. com/science/article/pii/ S0264410X19313647   to find the published study where that connection was discovered.  "The Department of Defense study was published in the July 2020 issue of  the prestigious journal Vaccine that demonstrated that flu shots were significantly associated with an increased incidence of subsequent  coronavirus (as well as metapneumovirus) infections."  What worries me the most is that aspartame is being put in drugs unlabeled.  I have stopped breathing 4 times now and am only alive by the grace of Jehovah God.  I have been misdiagnosed, treated for diseases I don't have and spent 3 months in the hospital.  They drugged me so much that I couldn't walk and was transferred to a rehab for 21 days because I could no longer walk.   When I came home, nurses and an excellent physical therapist were sent to help me.  The nurses couldn't understand why I refused all the medication.  I told them I knew there was aspartame in them and I would prove it by being the guinea pig and show that, without them, I could get well.  Today, I am free of the problems I had in the hospital from taking the aspartame-laced drugs, including having a heart attack which aspartame causes.  I am able to walk again and, as one nurse said, "You've made a believer of me".     One hospital admission was because I almost choked to death.  You read above from Dr. Roberts' medical text how aspartame swells the larynx.  Nobody has ever said it better than Dr. James Bowen who got ALS from aspartame when he told them it was mass poisoning of the US and 70 countries of the world, now probably 200.  Remember also that aspartame is a multi-potential carcinogen shown by the Ramazzini Studies by Dr. Morando Soffritti on rats and a Harvard Study on humans.  Even the FDA (Dr. Adrian Gross) admitted it to the Senate and said approval of aspartame violated the Delaney Amendment.  It was marketed by G. D. Searle who hired Don Rumsfeld to get it on the market after the FDA revoked the petition for approval.  See the documentary: "Sweet Misery: A Poisoned World".   Aspartame is now referred to as Rumsfeld's Plague.  So, that is what happened to me but it doesn't have to happen to you.   I wrote a Hospital Report with the chapter on aspartame and drug interaction from Dr. Roberts medical text.  Don't go to any hospital without it.  Print this out and keep it handy.  http://www.mpwhi.com/ aspartame_hospital_form.htm  I implore anyone who reads this report to send a copy of the above to your local hospitals, to the CEOs and top officials.  There is a report where Dr. Russell Blaylock explains what the hospitals can do to get people well, and maybe somebody will have the courage to do what is necessary.  Hospitals are under the domination of Big Pharma and even give physicians "pink slips" if they don't prescribe certain drugs like the dangerous statins. If everyone who reads this report will at least do send it to one hospital, we can make a difference and maybe save thousands.  Pass it on to your lists, family and friends and stay safe.  Renowned Dr. Russell Blaylock says, "The evidence strongly suggest that hospitals can easily control this cytokine storm by using very large dose intravenous vitamin C and Curcumin, both of which has shown high levels of rapid recovery from the effects of this virus induced cytokine storm."   A cytokine storm is an overproduction of immune cells and their activating compounds (cytokines), which, in a flu infection, is often associated with a surge of activated immune cells into the lungs. The resulting lung inflammation and fluid buildup can lead to respiratory distress and can be contaminated by a secondary bacterial pneumonia -- often enhancing the mortality in patients.   He suggests for those at home to help  their immune system use Curcumin and white tea.    He is author of many books on aspartame including "Excitotoxins: The Taste That Kills".  The hospitals should listen to Dr. Blaylock.  I credit him with saving my life when I had pneumonia many years ago.   No antibiotic would work so they were sending me home to die because if a hospital can't help they can't keep you.   He wanted the doctor to use Vitamin D, 10,000 I.U.  Several days later, the pneumonia was gone and the doctor said "he saved your life".  He is not only a retired neurosurgeon but also practiced as a nutritionist for 3 years.  His books are truly dynamic knowledge and he is also the author of the Blaylock Report.  I'll conclude with comments from Stephen Fox, Mission Possible New Mexico who has done a great deal of research on the virus.  "My comments are limited, because these matters are far beyond the powers of anyone who has no official interrogatory or subpoena powers, nor officially approved academic qualifications, including most of the considerations about how it started, who started it and when, who will benefit economically from this pandemic, and was it truly biological warfare or some freak of nature, or as a predictable accident, as Dr. Francis A. Boyle puts it, a Harvard Law School graduate and professor of Law at the University of Illinois law school. I do know that the Czech Republic weeks ago mandated that everyone wear a mask, and they have had only two deaths from Corona virus, and I do know that my New Mexico Governor, Michelle Grisham Lujan, a former New Mexico Secretary of Health, and the present New Mexico Secretary of Health, Kathy Kunkel, who is also like the Governor a lawyer, have put together fierce restrictions which I believe have kept our death toll to only two, a man in his 70s andanother in his 80s, both with pre-existing pulmonary conditions.  Our stats are way below those of Texas, on a per capita basis, and significantly lower than Utah, Arizona, Colorado, and Nevada. It is quite significant that just a few months ago, Italians were marching in the streets because they objected fiercely to required inoculations for influenza...those dreaded 'flu shots' that everyone except me it seems lines up to get in the late fall.  The Italian government proceeded to force the people to get them...and now they have very high rates of coronavirus infection. Some are predicting that the US will see 200,000 deaths. All we can do at this point is hope and pray that they are wrong.  Dr. Martini is spot on in proving that anyone with a weakened immune system from their ingesting aspartame regularly, which is metabolized in everyone as formaldehyde and the proven brain tumor causing agent, diketopiperazine, that these people are going to have a tough time if not an impossible time, resisting corona virus in this enlarging epidemic. The epidemiologists are going to have a field day if and when this pandemic runs its course, analyzing corona vs smokers, junk food eaters, those vaccinated with the flu shots, and of course, those who have consumed aspartame. When the equation is stated like that, it makes me wonder whether this pandemic will ever end. Supposedly, it is winding down in China, and certainly the South Koreans have done the best job to curtail the effects of corona virus to date."  Dr. Betty Martini, D.Hum, Founder  Mission Possible World Health Intl  9270 River Club Parkway  Duluth, Georgia 30097  www.mpwhi.com  770 242-2599

http://www.mpwhi.com/aspartame_hospital_form.htm



Hospital Form For Vital Information To Be attached to my file
NAME________________________
ADDRESS ______________________________________________________________________________________
PHONE NUMBER_____________________________
CELL NUMBER____________________________________
ALLERGIES: ASPARTAME, NEOTAME, NUTRASWEET, AMINOSWEET, E-951, SPOONFUL,ADVANTAME, SUCRALOSE, CANDEREL, BENEVIA,ACESULFAME POTASSIUM ______________________________
Absolutely, emphatically no aspartame in any form is to be given to me. This means not in food or in drugs and generics must be checked as its in most generic gastrointestinal drugs. It should be noted that aspartame victims become chemically hypersensitive and can stop breathing, break out in urticaria or go into anaphylactic shock. Many carry epi-pens. A dietary history should be taken before being given drugs such as pain medication as reactions with aspartame can be severe.
OTHER ALLERGIES AND REACTIONS_______________________________________________________________________________________
____________________________________________________________________________________________________________________
THE REASON FOR THIS INFORMATION TO BE ADDED TO MY CHART IS THAT ASPARTAME IN ITS MANY FORMS IS IN DRUGS AS WELL AS FOODS. IT CAUSES CHEMICAL HYPERSENSITIZATION USUALLY IN ANYONE WHO HAS USED IT, THE REASON FOR SO MANY CASES OF DRUG INTERACTION AND SUDDEN CARDIAC DEATH - http://www.mpwhi.com/aspartame_and_sudden_death.htm
In the documentary, "Sweet Misery: A Poisoned World" https://www.youtube.com/watch?v=ZI7_8FDzuJE Cheryl Kemptner told her hospital not to give her aspartame. A dietitian gave her some lemonade, Crystal Lite , with it and you see she became a Code Blue and had to be resuscitated to save her life. In the movie you will hear from world experts that will answer many physician's questions. For a lot of info on aspartame and drug interaction: http://www.mpwhi.com/aspartame_interaction_with_drugs.htm In this particular post you will find a chapter from Dr. H. J. Roberts, "Aspartame Disease: An Ignored Epidemic" on drug interaction with aspartame and the mechanism by which is happens: http://www.mpwhi.com/interference_with_drug_reaction.pdf These pages are being printed out or will be added at the bottom for the hospital to attach to my file. If any drugs are prescribed by doctors in this hospital they must check the generics because this is what is filled because of the insurance industry. Aspartame is in many generics, especially gastrointestinal and aspartame triggers gastrointestinal disease.
From the front page of Time, August 7, 2017 :" Depression afflicts 16 million Americans, One-Third Don't Respond To Treatment". Aspartame is a psycho drug and interacts with all antidepressants. Article by psychiatrist Ralph Walton, M.D., who has done two studies on aspartame (depression and autism) writes about aspartame and psychiatric disorders: http://www.mpwhi.com/aspartame_and_psychiatric_disorders.htm
Medical texts from these experts should be part of every hospital's library:
"Aspartame Disease: An Ignored Epidemic", 1000 pages, by the late H. J. Roberts, M.D. http://www.amazon.com Dr. Roberts was a diabetic specialist and explains that aspartame can not only precipitate diabetes but it simulates and aggravates diabetic retinopathy and neuropathy, destroys the optic nerve from the free methyl alcohol, causes diabetics to go into convulsions and interacts with insulin. The methanol makes them lose limbs.
Peer reviewed studies document the problems: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772345
"Excitotoxins: The Taste That Kills" by neurosurgeon Russell Blaylock, M.D., http://www.russellblaylockmd.com Includes MSG as well as aspartame.
"While Science Sleeps: A Sweetener Kills", http://www.whilesciencesleeps.com by Dr. Woodrow Monte. Exposes the fact that the original teratology studies on aspartame were sealed which showed neural tube defects, spina bifida and cleft palate for starters. Dr. Monte explains the seriousness of free methyl alcohol. He took the issue of aspartame triggered seizures and blindness to the Supreme Court.
Doctors Roberts and Blaylock have other texts. There are many books like "Aspartame: King of Toxins" and can be found on http:?/www.amazon.com
Some hospitals purchase foods that may contain sucralose/Splenda:
The Lethal Science of Splenda: http://www.wnho.net/splenda_chlorocarbon.htm
Studies have shown that sucralose can:
*Cause the thymus to shrink by as much as 40% (the thymus is your immune powerhouse - it produces T cells)
*Cause enlargement of the liver and kidneys
*Reduce growth rate as much as 20%
*Cause enlargement of the large bowel area
*Reduce the amount of good bacteria in the intestines by 50%
*Increase the pH level in the intestines (a risk factor for colon cancer)
*Contribute to weight gain
*Cause aborted pregnancy low fetal body weight
*Reduce red blood cell count
Particular warning for diabetics: Researchers found that diabetic patients using sucralose showed a statistically significant increase in glycosylated hemoglobin, a marker that is used to assess glycemic control in diabetic patients. According to the FDA, "increases in glycosolation in hemoglobin imply lessening of control of diabetes."
Here is how Splenda is made: http://www.wnho.net/chemical_processing_of_splenda.htm
Recently, Dr. Morando Soffritti announced a study on Sucralose which showed it causes cancer.
A safe alternative sweetener made from organic food is "Just Like Sugar". It's made from organic orange peel and chicory. Chicory has been used for 70 years to improve the health of diabetics. It can be gotten from http://www.justlikesugarinc.com
Acesulfame potassium caused cancer and leukemia in original studies.
Aspartame goes by many names, NutraSweet, Equal, Spoonful, AminoSweet, Canderel, E951, Benevia and Neotame, for starters. The FDA has approved Advantame which is half aspartame. Neotame is not usually labeled. According to the FDA Advantame will only not be added to meat and poultry. So there is no sign it will be labeled. There is no PKU warning and Dr. James Bowen says it causes Phenylketonuria.
Most importantly there is no pregnancy warning and aspartame in original studies caused neural tube defects, spina bifida and cleft palate for starters. The studies were sealed from the public through a deal by G. D. Searle and the FDA. Autism is rampant. The last chapter discussing this issue in "While Science Sleeps: A Sweetener Kills" is free on http://www.whilesciencesleeps.com When Jerome Bressler involved in the aspartame investigation retired from FDA he asked help in finding the FDA information and studies about this situation sealed from his report. It has now been added back and you will see from FDA records they confess aspartame causes birth defects: http://www.mpwhi.com/complete_bressler_report.pdf
The Opioid Situation: Aspartame can react violently with opioids,. All hospital patients should be asked if they are using aspartame before being given opioids. Obviously aspartame has a lot to do with these deaths. It may not be an overdose. They may simply be using aspartame and death is the result of the interaction.
Michael Jackson a former Diet Pepsi spokesman is a classic example. He also had lupus, which is big time precipitated by aspartame. James Bowen, M.D. wrote: "The ability of methyl alcohol/formaldehyde to create antigenicity, especially as combined in aspartame molecules is so great as to cause severe autoimmune reactions to the tissues deformed by formaldehyde polymerization, adduct formation. The immune system turns against the victim's tissues: Lupus." Michael Jackson used Diet Pepsi and it was a no-brainer that in the end death could happen from interaction.
Example of drug interaction. Headache is #1 on the FDA list. http://www.mpwhi.com/92_aspartame_symptoms.pdf
If the victim goes to a physician he may be prescribed Maxalt. The pharmaceutical company has been alerted that aspartame causes headache and they have added it as an ingredient. They refuse to remove it so a study was done and it showed Maxalt made headaches worse. They refused. A study was done showing using Maxalt makes the patient worse and they still refuse to remove it.
This form has been prepared by Mission Possible World Health Intl, http://www.mpwhi.com Mission Possible is non-profit and a global volunteer force in over 40 countries educating the public that aspartame is a chemical poison and working to have it removed from the public. It has no place in a hospital to make the patient worse, and may have brought him to the ER because of it.
Signature________________________________________________________
Chapter on Aspartame and Drug Interaction below is copied from "Aspartame Disease: An Ignored Epidemic" by H. J. Roberts, M.D., a 1000 page medical text on symptoms and diseases precipitated or triggered by this addictive, excitoneurotoxic, carcinogenic, genetically engineered drug, adjuvant and teratogen. The damage to the mitochondria is what causes so many drug reactions. http://www.amazon.com

1. The author's clinical observations indicate that aspartame products can alter the action of important drugs. They include coumarin (Coumadin), phenytoin (Dilantin), antidepressants, other psychotropic agents, propranolol (Inderal), methyldopa (Aldomet), thyroxine (Synthroid), and insulin (Chapter XIII). This phenomenon is illustrated in many case reports presented in other sections.
It is also likely that some herbs interact with aspartame. Noting that numerous herb-drug interactions, Fugh-Berman (2000) stated, "Health care practitioners should caution patients against mixing herbs and pharmaceutical drugs."
General Considerations Alteration of the blood proteins to which drugs attach.Alteration of drug receptors on cell membranes.Changes in the sites at which impulses are transmitted along nerves and to muscle. Metabolic abnormalities in the elderly that are known to enhance their vulnerability to drug reactions (Weber 1986).This problem increases in the case of persons taking multiple drugs ("polypharmacy") prescribed by several physicians.Interference with drug action by amino acids and protein. An example is the erratic therapeutic effects when patients with parkinsonism who were controlled on levodopa began to use aspartame products (Chapter VI-J). The antagonism if levodopa by dietary protein presumably reflects impaired transport from serum across the blood-brain barrier by neutral amino acids (Pincus 1986).
The methanol component of aspartame (Chapter XXI) might interact with compounds containing ethanol. Examples include the hypoglycemic sulfonylureas, metronidazole (an antibacterial drug), and allopurinol (commonly used in the treatment of gout). In his review of this subject, Posner (1975) emphasized that such interactions pose "an important area for careful clarification."
Drug Reactions After the Cessation of Aspartame
The phenomenon of increased sensitivity to a drug after the removal of some interfering factor is known to clinicians. Examples include severe insulin reactions in diabetics after cure of an infection, and bleeding from coumarin after terminating a drug that influenced its binding to carrier proteins. This type of encounter probably reflects an increase in the "Free" forms of such drugs, It occurred, for example, when patients on maintenance coumarin or phenytoin avoided aspartame.
A. Coumarin (Coumadin)
Coumarin is commonly prescribed as a anticoagulant ("blood thinner") for the treatment or prevention of serious problems caused by thrombosis (clot formation) and embolism (the migration of a thrombus). The vascular beds frequently affected include the coronary arteries, the carotid arteries, the inner lining of the heart (endocardium) in patients with heart attacks or irregular heart action (atrial fibrillation) from which embolism to the 7brain or lower extremities may originate, and veins in the lower extremities and pelvis that are frequent sites for pulmonary emboli.
This form of therapy constitutes a major commitment for physicians, particularly the need for continually monitoring the prothrombin time. Patients may bleed if the anticoagulant effect becomes excessive. Conversely, the loss of desired anticoagulation invites recurrence of thrombosis of embolism.
The likelihood of interference by aspartame was raised in patients who had been maintained on coumarin for extended periods with difficultly. Unexpectedly, their prothrombin times approximated the control values (meaning a loss of anticoagulant effect), coupled with recurrent thrombophlebitis or angina pectoris.
Representative Case Reports
Case IX-I-I
An 82-year-old woman had received coumarin for two reasons: recurrent transient cerebral ischemic attacks ("small strokes") due to embolism from the carotid arteries, the heart, or both; and severe thrombophlebitis in the lower extremities with multiple attacks of pulmonary embolism. A registered nurse administered her medication daily.
The patient's prothrombin time, monitored every 3-4 weeks, had remained stable a long time. It was found to only 14 seconds (control, 13 seconds) on August 19, 1986. Several days thereafter, she developed severe pain in the lower extremities and exquisite tenderness over the deep veins, consistent with recurrent thrombophlebitis. The dosage of coumarin was increased.
On direct injury, it was determined that she recently began to use aspartame products. These were discontinued. Three days later, blood was noticed in the urine. At that time, her prothrombin time had returned to the therapeutic range - namely, 21 seconds. Coumarin was withheld several days. The failure of urinary bleeding to recur when coumarin was then resumed probably reflected a return of full anticoagulation after the loss of aspartame interference.
Case IX-I-2
A 72-year-old woman had been treated with coumarin for longstanding angina pectoris and thrombophlebitis. Her prothrombin times generally ranged between 19.5-22 seconds. The patient then developed unstable angina pectoris and rapid heart action (tachycardia) for which she was hospitalized. No precipitating cause could be determined. At the time, little significance was paid to the slight decrease of her most recent prothrombin time (17 seconds). Even though the dosage if coumarin was increased, the prothrombin time then declined to 15 seconds.
The occurrence of other complaints suggesting aspartame disease raised the question as to whether aspartame also had influenced the prothrombin time.
They included severe "burning and swelling" of the lips and tongue, headache, increased visual difficulty (despite recent cataract surgery and prescription glasses), marked "nervousness," and unexplained nausea. Although she initially denied using aspartame, the "diet" ginger ale she drank did contain it. The prothrombin time rose to 22 seconds (control, 12 seconds) one week after shopping aspartame. During this time, her intense fatigue and lip-tongue reactions subsided.
B. Phenytoin (Dilantin) and Other Antiepileptic Drugs
Phenytoin is a key in managing epilepsy. When convulsions are associated with or aggravated by aspartame products (Chapter III), the patient confronts several dilemmas. First, the dose of phenytoin is likely to be increased, possibly to the point of toxicity (see Case III-35). Second, other anti-epilepsy drugs may be added, thereby increasing the potential for side effects. Third, the continuation of these drugs in high doses could result in "rebound" toxicity after stopping aspartame.
The apparent potentiation of valproic acid (Depakene; Depacote), another antiepileptic drugs, was personally reported to the author by a 51-year-old man who drank considerable diet cola daily. When his physician increased the dose, he became comatose and required hospitalization.
Representative Case Report
Case IX-I-3
A 28-year-old man suffered seizures after a head injury while serving in the Marines. As a civilian, his convulsions unexpectedly increased despite multiple anti-epileptic medications, causing him to lose his job.
The patient's mother noted that he "acted like he was intoxicated." She expressed concern over his large consumption of aspartame sodas. Shortly after discontinuing them, he had to be taken to an emergency room for phenytoin intoxication - presumably representing the rebound phenomenon.
C. Antidepressant Drugs
Aspartame may interfere with the action of important drugs used to treat depression, particularly imipramine (a tricyclic antidepressant). Others have made similar observations.
Walton (1986) described a 54-year-old woman with recurrent major depression who had been well controlled on a maintenance dose of 150 mg imipramine at bedtime. She subsequently experienced marked behavioral changes, manic behavior characterized by inappropriate euphoria and flighty ideas, and a grand mal seizure. It was then learned that she had been drinking considerable aspartame-sweetened iced tea for several weeks prior to the seizure. All evidence of manic activity subsided within four days after stopping aspartame and the addition of lithium. Her depression recurred, however, two months later. Imipramine was resumed at the previous dosage with no recurrence of severe depression or mania over the ensuing 13 months.
The monoamine oxidase inhibitors (MAOIs), another group of antidepressant drugs, can have additional adverse effects when aspartame is consumed. These include phenelzine (Nardil), isocarboxazide (Marplan), and tranylcypromine (Parnate).
It is pertinent that hypertensive crisis have occurred in patients so treated after they consumed foods and beverages containing tyramine and tryptophan. This response probably represents vasospasm caused by amino acid-derived sympathomimetic substances such as norepinephrine and tyramine (Chapters IX-C and XXIII).
The serotonin-elevating action of fluoxetine (Prozac) for treating depression could be counteracted by aspartame. It can block tryptophan entry to the brain, thereby inhibiting synthesis of serotonin (Chapter VII).
A Minnesota physician called to inquire about a possible interaction between Prozac and aspartame. He had suffered depression for which Prozac was prescribed, but without much benefit until he avoided aspartame. At what point, the drug proved helpful.
D. Propranolol (Inderal)
The occurrence or aggravation of benign ("essential") tremor by aspartame was described in Chapter VI-J. This condition usually can be controlled with small or modest doses of propranolol. Several patients and correspondents stressed that their tremor intensified after consuming aspartame - even with increased dosage of propranolol - and improved when they avoided when they avoided such products.
E. Thyroid Replacement Therapy
The increased susceptibility of hypothyroid to aspartame (Chapter IX-E) has been repeatedly emphasized. Conversely, there may be interference with the activity of thyroid replacement therapy.
Case IX-I-4
An aspartame reactor had been taking thyroid hormone several years. After avoiding aspartame products, he noted "My replacement thyroid dose, which had been steadily increasing for the last few years, dropped by 30 percent. My doctor was quite surprised, and had no other explanation for it".
F. Female Hormone Replacement Therapy
Patients with aspartame disease expressed firm convictions about interactions involving female hormone replacement therapy.
Representative Case Report
Case IX-I-5
A 40-year-old saleswoman consumed considerable diet sodas and other aspartame products, especially during the summer. She supplemented her description of reactions in the survey questionnaire with a two-page analysis of major changes when taken in conjunction with Premarin/Provera. They included cloudy vision, dizziness, tenderness and tingling of the feet, joint pains, numbness of the lower limbs, headache, "foggy thinking," confusion, slurred speech and extreme fatigue. She took as many as 18 ibuprofen tablets daily to obtain relief of her constant pain. Extensive neurologic studies - including electromyography, nerve conduction studies, x-rays and MRI scanning - failed to revel a cause.
Considering a possible connection to the hormonal therapy, she reduced Premarin by half and quit Provera. There was considerable relief from the joint pain and muscle aches within two days, along with cessation of her neuropathic symptoms. After then avoiding all aspartame products, she wrote, "I felt IMMEDIATE relief within two days of what remained of the lumbar ache, muscle aches, foggy thinking, dizziness, and cloudy vision. All these improvements continue in the week since. Walking seems less of an effort; hip pain improved."
G. Methyldopa (Aldomet)
There have been references to enhancement of seizures and other disorders in patients receiving methyldopa hypertension who also consumed aspartame. Seven of the initial 397 reactors completing the questionnaire were taking this drug when they experienced aspartame disease. Maher and Kiritsy (1987) demonstrated that aspartame administration decreases the entry of methyldopa into rat brain.
Representative Case Report
Case IX-I-6
A 67-year-old retired hypertensive woman had been treated with methyldopa. She experienced three unexplained seizures while drinking one can of diet cola and eating various aspartame puddings daily. The convulsions stopped when she avoided aspartame products, as did her sensitivity to noise and attacks of rapid heart action.
H. Analgesics
Lidocaine (Xylocaine) is an important drug used for local anesthesia and the treatment of ventricular arrhythmias in intensive care units. Alterations of its pharmacology by aspartame require study.
Kim et al (1987) reported that the intraperitoneal administration of aspartame significantly reduced the 50 percent convulsion dose of lidocaine. They indicated that PKU patients and asymptomatic PKU heterozygotes may be more sensitive to the toxic effects of this and related local anesthetics.
Nikfar et al (1997) noted that aspartame increased morphine analgesia in the early phase (wherein saccharin had no effect), and further enhanced morphine analgesia during the late phase. The sister of heavy diet cola consumer related the apparent potentiation of morphine by aspartame while he continued drinking it in an intensive care unit after a heart attack. This interaction became evident when the aspartame was stopped, coupled with halving the insulin required for managing his diabetes.

Bone marrow and lymph nodes, the organs chiefly responsible for blood cells, are highly vulnerable to toxic substances. For example, aplastic anemia and leukemia may occur after treatment with potent drugs, or exposure to pesticides and other chemicals in the environment (Roberts 1984, 1990b). Aspartame products could be another cause of disorders therein.
A. Bone Marrow and Blood Changes
Aspartame disease may be evidenced by changes involving red blood cells, white blood cells and platelets. The aspartame reactors reported below and elsewhere evidenced either anemia, a striking elevation of the white blood cell count suggestive of leukemia, or markedly decreased platelet counts (thrombocytopenia).
A patient with recurrent "histiocytic leukemia" following aspartame ingestion (Case IX-J-1) offers an intriguing clue to the so-called histiocytosis syndromes in children (The Lancet 1987; 208-209). The Langerhans cell in histiocytosis is a dendritic cell derived from the bone marrow.
Many drugs and other substances have been implicated in "immune thrombocytopenia."
Case IX-F-6 mentioned the finding of "enlarged red blood cells." Deficiency of folic acid or its altered metabolism (see below) causes macrocytic (large red blood cell) anemia, while deficient absorption of vitamin B12 can result in a similar anemia.
Patients with pernicious anemia may be more vulnerable to aspartame. For example, a 51-year-old woman with severe aspartame disease gave a history of treatment for documented pernicious anemia as her only significant past medical history.
Representative Case Reports
Case IX-J-I
A 10-year-old girl began consuming various aspartame products at the age of eight, initially during summer weekends. She developed marked swelling of one shoulder which then involved the neck. Her arm almost tripled in size. There was no history of allergies or aspirin use existed. The patient also evidenced a high fever, pleural effusion (fluid in the lung cavity), striking enlargement of both the liver and spleen, and a precipitous decline of the platelet count to 1,000 per cubic mm (normal 150,000 or higher). A striking increase of histiocytes was found in her bone marrow. Several "liver enzymes" were markedly elevated - i.e., SGOT 3,080 units/L (normal, up to 50); CPK 30,000 units/L (normal, up to 50).
Numerous physicians and consultants saw this child. Most diagnosed histiocytic leukemia. The patient received large doses of Prednisone.
Dramatic clinical improvement and virtual normalization of the foregoing blood changes occurred when the mother closely monitored her diet and eliminated additives. The Prednisone was then stopped.
The patient subsequently ate several bowls of an aspartame cereal. Marked swelling of the cheeks developed, coupled with recurrence of the aforementioned features. When aspartame was discontinued, the swelling receded without prednisone.
Several months later, the girl was given aspartame chewing gum without the mother's knowledge. Swelling of her entire body, recurrent enlargement of the liver and spleen, a dramatic increase of bone marrow histiocytes, and severe pain in many joints ensued. Total abstinence from aspartame again effected the disappearance of her symptoms and the blood abnormalities within six months. At the time of my last discussion with her mother, the child had minimal enlargement of the liver, and was receiving Prednisone in low doses only intermittently.
This patient had two sets of head x-rays, three CT scans of the brain, two spinal punctures, four bone marrow studies, two electroencephalograms, two heart monitoring studies, two barium enemas, and a host of other studies. Her mother estimated the medical costs at $750,000!
Case IX-J-2
A 62-year-old man developed severe gastrointestinal problems while ingesting aspartame products. He developed "an erratic blood count, with red and white cell imbalance, and platelets off some." He received "cortisone" for six months when his condition was diagnosed as "an immune deficiency problem."
His daughter suffered intense abdominal pain, a bleeding peptic ulcer, severe headache, and repeated grand mal convulsions when she used aspartame products. A granddaughter had Phenylketonuria (Chapter XVII) at birth, and subsequently manifested severe learning deficiencies.
Case IX-J-3
A 61-year-old personnel director began drinking diet colas at the age of 59, and consumed up to one liter daily. His platelet count declined to 54,000/cu mm thereafter. He also became concerned over "forgetting to perform things for which I was responsible." Other complaints included "double vision," severe sensitivity to light, headache, dizziness, two convulsions, "fits without convulsions," marked sleepiness during the day, insomnia, slurred speech, and a nonspecific rash. Extensive studies failed to uncover a major medical problem.
His symptoms improved within 10 weeks after avoiding aspartame, although some problems with vision, memory, sleep and "concentration" persisted. There was an immediate exacerbation during one retest trial. After avoiding all aspartame products, the platelet count had increased to 75,000/cu mm at the time of his subsequent correspondence.
Case XI-J-4
A registered nurse developed hypertension and a platelet count under 30,000 during her third pregnancy. Neither of these features had been noted in previous pregnancies. She began using diet colas after the birth of her second child. Other symptoms included severe headache, depression, loss of hair, and symptomatic reactive hypoglycemia.
Case IX-J-5
A 41-year-old woman consumed diet cola for 14 years. She experienced many symptoms of aspartame disease for three years, including headache, visual problems, severe aching of the joints, numbness of the left hand, and easy agitation. Her white blood cell count was only 460 (normal 4000-10,000), for which no other cause could be determined.
B. Lymph Node Enlargement
Enlargement of the lymph nodes (lymphadenopathy) occurred in several aspartame reactors without the finding of another convincing cause. This featured differed from the striking salivary gland enlargement in other with aspartame reactors (Chapter IX-D).
Representative Case Reports
Case IX-J-7
A mortgage broker began drinking diet cola in January 1995. She developed markedly enlarged glands in the neck ("the size of golf balls") one year later, along with a constant sore throat. These features persisted despite considerable doctoring. Subsequent symptoms included blurred vision, migraine headaches, severe joint and muscle pains, constant diarrhea with bloody stools, ringing in the ears, palpitations, night sweats, "a tongue as black as leather," a 30-pound weight gain, and "incapacitating" chronic fatigue. Various suggested diagnoses - including carbon monoxide poisoning, fibromyalgia, lupus erythematosus, and Epstein-Barr infection - could not be confirmed.
The patient was "absolutely in shock" on learning about aspartame disease. Improvement proved gratifying after discontinuing aspartame products. The tongue returned to a normal healthy pink state. The enlarged glands in her neck decreased within several months.
Case IX-J-8
A 44-year-old loan officer experienced headache, drowsiness, hyperactivity, severe tingling, irritability, personality changes, palpitations, a recent elevation of blood pressure, abdominal pain, itching, hives, other rashes, marked frequency of urine, and joint pains. These symptoms were provoked "immediately" on three retesting trials with aspartame products.
His son had aspartame disease. It was primarily evidenced as "noncancerous lumps under the arms" and a rash.
C. Altered Folic Acid Metabolism
Aspartame may deplete important nutrients related to folic acid. Folic acid assists in eliminating the formic acid derived from methyl alcohol degradation (Reitbrock 1971). It tends to decrease with higher methanol concentrations (Chapter XXI). In view of the rarity of low blood foliate levels in contemporary clinical practice, this finding could prove a clue to aspartame disease.
Aspartame-induced decrease of folic acid could have clinical significance, especially anemia and birth defects.
A physician in the State of Washington noted anemia in a patient who ingested large amounts of aspartame sodas, and suspected folic acid deficiency. He found the blood methanol level to be elevated. Unfortunately, the tube sent for a foliate level broke in transit after he started replacement therapy.
There has been a recent impressive decline in neural-tube following the fortification of grain products an vitamin formulations with folic acid, coupled with an associated increase of median serum foliate concentrations. This decline might be less evident, however, among pregnant women who consume aspartame products that can deplete foliate levels as methyl alcohol is metabolized.

The vulnerability of patients with pre-existing liver disease to aspartame was noted in the introduction of this section. These disorders include hepatitis, cirrhosis (Case IX-K-5), hemochromatosis (iron storage disease), and the liver dysfunction complicating many infections and drug reactions.
Several aspartame reactors without known liver disease evidenced marked elevation of blood aminotransferases ("liver enzymes"). They are variously referred to as alanine aminotransferases (ALT; SGPT), aspartate aminotransferase (AST; SGOT) and glutamyl transpeptidase (GGT). (Serum levels of ALT and AST in normal persons are less than 35units/L. In Case IX-J01, a 10-year-old girl, the SGOT was 3,080 units/L. One such aspartame reactor had been told, "Your liver is pickled."
Monte (1984) made a reference to such an association. Taylor (1996) also raised the issue of liver toxicity caused by aspartame in a 51-year-old man who evidenced repeated jaundice.
General Considerations
In a recent National Health and Nutrition Examination Survey, 2.6 percent of the United States population surveyed had elevated serum ALT for which no cause of chronic liver disease could be found (James 1999). Even though 70 percent of the adult population consumes aspartame products, aspartame disease was not suspected as a likely causative or contributory cause. It is of historic interest that Dr. Misael Uribe (1982) expressed concern that the FDA had not adequately considered the potential toxicity of aspartame patients with liver disease shortly after its forthcoming release was announced.
Persons with cirrhosis of the liver are at increased risk because they may be unable to metabolize aspartame and its breakdown products adequately (Jagenberg 1977; Herberer 1980; Dhont 1982).
The possibility of aspartame toxicity should be entertained in patients diagnosed as having nonalcoholic steatohepatitis. This liver disorder has become a common liver disorder in North America, and can progress to cirrihosis (James 1999). Its frequent features of persistent fatigue, upper abdominal discomfort, diabetes and hyperlipidemia are also encountered in aspartame disease.
Obese persons and diabetic patients who consume considerable aspartame appear to be at higher risk for the development of chronic nonalcoholic steatohepatitis, especially when addicted to such products (Chapter VII-G). The term "nonalcoholic" is misleading in this instance because aspartame contains ten percent methyl alcohol.
Admittedly, it may be difficult to single out precise symptoms attributable to aspartame products in patients with liver disease. Yet, few physicians considered the contributory role of aspartame to hepatic changes among patients in this series. Some even were hostile to the idea (see Case IX-K-3).
By contrast, astute persons and various consumer groups submitted related observations to the FDA. The husband of one patient, an attorney, became irate over the absence of any wearing labels on aspartame products for persons with liver disease.
Representative Case Reports
Case IX-K1
A 68-year-old housewife described how she became "incapacitated" form aspartame products in these terms: "My eyes would not focus. I had confusion, dizziness, depression, insomnia and memory loss. I could not drive or leave the house alone." Other complaints included severe nausea, diarrhea, marked thirst, considerable frequency of urination, and attacks of hypoglycemia. Her "liver reading" (presumably the ALT) rose from 44 to 264. It declined to 78 after she avoided aspartame. Although her physician assumed it was due to "drinking," the patient empathically stated that she never drank alcoholic beverages.
Case IX-K-2
A prospective blood donor was surprised, and angered, when a blood bank would not accept her blood (SGOT and SGPT) were markedly elevated. She consulted a gastroenterologist. He confirmed the finding, and by exclusion diagnosed hepatitis C infection. Abdominal ultrasound studies and other tests were normal. Aside from advice to stop her modest drinking, the only other treatment option offered was interferon. She declined the latter because of its inherent severe side effects.
Her teats remained unchanged over the next two years despite total abstention from alcohol. She would not kiss persons for fear of transmitting the presumed infection.
A friend commented that aspartame products could harm the liver. As personal proof, she pointed to the normalization of her own blood studies after discontinuing diet sodas. The patient thereupon discontinued such products - including the seven packs per day (!) of aspartame chewing gum. A dramatic decline of her liver enzymes ensued.
Overwhelmed by this experience, she reported her case to the FDA and criticized its approval of aspartame as "total disregard for human health and safety."
Case IX-K-3
A man had consumed 24-60 ounces of diet sodas daily for a year while on "a very low calorie diet." He experienced numbness of his left hand, left foot, face, and then the right hand. Two MRI studies and other neurologic tests were normal. His liver enzymes, however, were elevated (GGT 350; SGOT 150); repeat testing confirmed these abnormalities. A CT scan of the liver and an ultrasound study of the abdomen were not revealing.
This patient was scheduled for consultation with a gastroenterologist. Learning about aspartame disease in the interim, he stopped aspartame products, and consumed considerable filtered water "in an attempt to flush my liver." Repeat liver tests evidenced progressive declines of the GGT to 15, and of the SGOT to 50. The gastroenterologist disregarded these observations, and criticized the patient's inference about aspartame being a possible cause.
Case IX-K-4
The 28-year-old manager of an architectural firm, and mother of a six-month child, had markedly elevated liver enzymes for four years, the cause of which eluded multiple physicians. Her AST, ALT and alkaline phosphates levels average 200, 200 and 1100, respectively. The bilirubin levels remained normal.
She never used drugs of abuse or smoked, and had not ingested alcohol for three years. No birth control pill was used since the age of 21. Numerous studies for hepatitis and HIV viruses, and for various auto-immune diseases were negative. In addition to multiple CT scans and an MR study, two liver biopsies proved normal.
The patient had "practically lived on" diet cola for ten years... "drinking more than water or any other beverage." This soda was avoided during pregnancy.
After reading about aspartame disease, she stopped all diet products. There was a prompt and striking decrease of all the enzymes, which progressively normalized with no other interventions.
Case IX-K-5 (FDA Project #3898; Courtesy, Dr. Linda Tollefson)
A 76-year-old woman with longstanding cirrhosis died in progressive "liver coma." In his correspondence to a consumer advocate, her husband indicated that she had been "in pretty good health" until October 1983 when an elevated blood glucose concentration was found. Tolbutamide and diet were prescribed. In an attempt to avoid sugar, she used four packets of an ATS daily in coffee, cereal and desserts
The patient evidenced dramatic deterioration within two weeks. It was manifest by indifference to her surroundings, forgetfulness, slurred speech, dizziness, impaired vision, loss of interest concerning food and her favorite television programs, and a change in gait. She made irrelevant statements as if hallucinating. Her condition deteriorated to the point of becoming incontinent and bedridden. A diagnosis of "hepatic encephalopathy" was made.
Related Biochemical Aspects
Deterioration of brain function in patients with severe liver disease has been attributed to the retention of phenylalanine and other amino acids (Fischer 1971). Striking changes in amino acid metabolism are known to occur in liver disease - particularly the hydroxylation rates of phenylalanine, tyrosine and tryptophan. The elevated phenylalanine concentrations in patients with cirrhosis rise significantly after protein consumption (Fernstrom 1979). Methanol poisoning (Chapter XXI) creates another serious problem in patients with liver disease. The enzymes alcohol dehydrogenase and aldehyde dehydrogenase are involved in methanol metabolism. The considerable alcohol dehydrogenase activity of the liver decreases when it is diseased.
One mechanism may be the production of tumor necrosis factor (TNF)-a. It is an early event in many types of liver injury that triggers the release of other cytokines, and then the destruction of liver cells.
A vicious cycle involving aggravated hypoglycemia also can occur. Contributory causes include the tendency to "hepatic hypoglycemia" among persons with severe liver disease (owing difficulty in storing and metabolizing glycogen), aspartame-induced hypoglycemia (Chapter XIV), the use of glucose-lowering drugs for control of diabetes, and the failure of diabetics receiving such drugs or insulin to take interval feedings. For example, the physician who prescribed tolbutamide for Case IX-K-4 "said nothing about diet."
Hemochromatosis (iron storage disease; hepatic iron overload; bronze diabetes) might be aggravated in its pre-cirrhotic stage by aspartame consumption (see Case XIII-1), especially through insulin stimulation (Chapter XIV). Related features of insulin resistance - in addition to hyperinsulinemia - are increased body mass, elevated lipids, and abnormal glucose tolerance.
The separate entity of primary hepatic iron overloads differs from genetic hemochromatosis because transferring saturation is normal, as is the frequency of the HLA A3 genotype (Ferrannini 2000). It has been suggested that insulin's primary action in stimulating glucose transport is coupled with a redistribution of transferring receptors to the cell surface where they mediate extracellular iron uptake.
Martini: This is the end of the chapter. by H. J. Roberts, M.D. Please also see the Aspartame Resource Guide: http://www.mpwhi.com/aspartame_resource_guide.pdf New study shows aspartame may be contributing to the end of human civilization, depletes transmitters in the brain: https://rense.com/general96/new-shows-study-aspartame-depletes-neurotransmitters-in-the-brain.php Epileptic patients complain aspartame is a seizure triggering drug and they are adding it to anti-seizure medication: https://rense.com/general96/aspartame-and-msg-now-in-neurological-drugs.php Check out the Aspartame Toxicity Center, http://www.holisticmed.com/aspartame